As the science and culture museum at Michigan State University and Michigan's land-grant university museum, the MSU Museum is committed to understanding, interpreting, and respecting natural and cultural diversity through education, exhibitions, research, and the building and stewardship of collections that focus on Michigan and its relationship to the Great Lakes and the world beyond. The MSU Museum is a public steward for nearly a million objects and specimens in natural science, cultural, and historical collections from around the world. The collections provide the foundation for research, education, and outreach both locally and internationally. It is one of the earliest established museums in the nation and has continued to preserve collections and serve learners since its opening on the campus in 1857. It is accredited by the American Alliance of Museums and was the first museum in the state to receive Smithsonian Affiliate status.

Every year in April, over the course of multiple days, the MSU Science Festival invites the public to experience more than 250 presentations and hands-on activities on the MSU campus and at venues across the state. There's something for everyone at the Science Festival, with presentations geared for all ages and interests. The mission of the MSU Science Festival is to celebrate the many ways science, technology, engineering, art, and mathematics (the STEAM disciplines) touch our everyday lives and shape our future. The 2020 Festival was virtual and the 2021 Festival will be as well.